Erectile dysfunction is a violation of male reproductive system which makes achieving and maintaining normal erection almost impossible. Currently, an obsolete term ‘impotence’ in medicine was replaced by a broader concept of erectile dysfunction. This pathology is characterized by an inability of a male to enter his penis into the partner’s vagina.
The pioneer of PDE-5 inhibitors – sildenafil citrate – the active ingredient of Caverta, heralded the new era in the treatment of erectile dysfunction, the era of extremely effective perioral drugs treatment. Sildenafil is a selective PDE5 inhibitor, which cleaves cGMP. When nitric-oxide metabolism is activated (occurring during sexual stimulation), the inhibition of PDE5 aims at preventing the collapse of the c-GMP, which is the final and most active component that stands for the development of an erection.
Caverta meets all modern requirements of a medication for treatment of erectile dysfunction. The drug represents a highly effective and reliable tool for oral administration. Even though the medication is easy to use and it has virtually no side effects; it is noted that the systemic manifestations, although they are transient, nevertheless, have a certain impact on the health of the patient, especially in case of large doses treatment.