Caverta

pic09Erectile dysfunction is a violation of male reproductive system which makes achieving and maintaining normal erection almost impossible. Currently, an obsolete term ‘impotence’ in medicine was replaced by a broader concept of erectile dysfunction. This pathology is characterized by an inability of a male to enter his penis into the partner’s vagina.

The pioneer of PDE-5 inhibitors – sildenafil citrate – the active ingredient of Caverta, heralded the new era in the treatment of erectile dysfunction, the era of extremely effective perioral drugs treatment. Sildenafil is a selective PDE5 inhibitor, which cleaves cGMP. When nitric-oxide metabolism is activated (occurring during sexual stimulation), the inhibition of PDE5 aims at preventing the collapse of the c-GMP, which is the final and most active component that stands for the development of an erection.

Caverta meets all modern requirements of a medication for treatment of erectile dysfunction. The drug represents a highly effective and reliable tool for oral administration. Even though the medication is easy to use and it has virtually no side effects; it is noted that the systemic manifestations, although they are transient, nevertheless, have a certain impact on the health of the patient, especially in case of large doses treatment.

The causes of erectile dysfunction

Official medical statistics shows that every year the number of men suffering from erectile dysfunction keeps on growing. The causes of this disease are divided into two groups: physiological and psychological.

Mentioned below is the list of psychological causes of impotence in men:

  • depression
  • the presence of constant stress
  • problems of interpersonal interaction between sexual partners
  • psycho-emotional trauma
  • overworking

For physiological reasons contributing to the emergence of impotence in men, include the provision of:

  • diseases of the cardiovascular system
  • disruptions of the endocrine glands (hormonal failure)
  • inflammatory processes in the urogenital system (inflammation of the kidneys, bladder, urethra, prostate)
  • ported injuries of the penis and the spine, and operations on the pelvic organs
  • consequences of receiving other drugs

However, all of these physiological disorders and injuries are not moved exhausts all cases and causes of erectile dysfunction.

The same medical statistics show that erectile dysfunction in men of 35-40 years there is observed in almost 40% of cases. In addition, it is necessary to take into account the fact that many men with impotence due to various reasons don’t tend to seek medical care, so the real frequency of the disease is likely to exceed 40% number.

According to statistics, most often the doctors are attended not by men suffering from erectile dysfunction, but by their wives, which encourages the husband to pay a visit to the doctor and start erectile dysfunction treatment.

Many women in marriage believe that erectile dysfunction in the husband is a problem of a particular individual, which is supposed to be resolved on his own. But this is a mistaken strategy, because in many cases the source of erectile dysfunction is husband’s wife.

In most of the psychological causes of erectile dysfunction the decisive factor is wife’s behavior. There is a large group of women, brutally using their husbands’ inadequacy in sexual relations, keeping in mind that husband’s bad potency makes a husband feels guilty and he therefore to be rehabilitated, thus it’s the right time to get a compensation in other spheres of life.

Fortunately, a range of quick and effective remedies has entered the market a couple of decades back, allowing the situation not to go that far. Sildenafil citrate, the active component of a range of medications provides the desired, pronounced effect on male reproductive organs, enabling a person to live a full life. Looking to get a truly effective drug at a fair and reasonable price? Buy caverta online to make the most of your sexual experiences.

Testimonials

Derek Rhody, 60 years old, Sydney

I am 60 years old and doubted the efficacy of Caverta. In fact, I purchased the pills almost accidently; but with the first dosage I feel like a sex giant. The results far exceeded my expectations, and my younger wife told me she was in heaven.

Martin Johnson-Price, 42 years old, Boston

Our relationship almost collapsed, at some point after five years of marriage our family life was almost doomed to failure. A recommendation of a friend saved my family – I’ve started feeling young again, and I am extremely happy that the problems in the intima didn’t bring us to divorce. The price is acceptable, the effect comes fast, nothing left to be desired. Thank you.

Jack Witfrield, 35 years, Birmingham

My wife and I have collided with problems in sexual life on a regular basis. With time, an average sexual intercourse has turned into a nightmare. Luckily, Caverta lent a helping hand just when it was needed most. By the way, see no difference between the pills and Viagra, that costs crazy money.

Dan Mastaart, 40 years old, Cardiff

More than pleased with Caverta action: no side effects and a truly miraculous effect every man will certainly enjoy. The cost is acceptable enough (even in comparison with Cialis), highly recommended.

Christopher Elm, 59 years old, Miami

The magnificent drug came to the rescue numerous times – finally, I’ve managed to refresh a taste for life making my wife happy, I’m 59 and take the drug on a regular basis. Thank God, no side effects so far.

Marcus Dumount, 29 years old, Perth

A silver bullet for my sexual failures has finally been found – Caverta is definitely a way to go! A lightning-speed effect in conjunction with an indescribable influx of energy is something that drives you crazy with insatiable hunger pulsating throughout your body. Top stuff, and yes, Levitra is a no match.

Side effects

Caverta is contraindicated in case of individual intolerability to the formulation components. The drug is allowed to use under the supervision of a physician in case of:

  • the presence of defects in the structure of the penis (especially with tissue defects),
  • blood diseases (anemia of certain forms, leukemia and some other ailments)
  • frequently observed bleeding – ulcers of the gastrointestinal tract in the phase of activation
  • liver dysfunction, especially the diseases that destroy the liver
  • kidney diseases influencing their performance
  • low/high blood pressure
  • previous heart attacks or strokes,
  • severe heart diseases

The emergence of migraine pain, dizziness, redness of the cheeks, temporary blindness, pain in the eyes is too much light, as well as a sense of veil before the eyes accounts for the 15% of the most widely spread side effects. Discomfort in the nasopharynx, diarrhea or other digestive disorders are observed in three percent of patients. Revitalization of the pathogenic microflora of the urogenital system was observed in two percent of cases. The appearance of hives or other skin reactions is noted in two percent of cases.

Clinical trials

In a study of Sairam group, the effect of sildenafil on the severity of LUTS in patients with erectile dysfunction has been evaluated. After 1 and 3 months after initiation of treatment a significant reduction in the severity of lower urinary tract symptoms, which was accompanied by an improvement in erectile function, was monitored.

The administration of Cavtera leads to the improvement of patients with primary and secondary pulmonary hypertension. In several experimental studies carried out on animals, a decrease of pressure in the pulmonary trunk with the introduction of sildenafil citrate was noted.

This fact has become a prerequisite for exploring the possibilities of Caverta in the treatment of pulmonary hypertension. Dr. Michelakis investigated the effects of oral sildenafil in patients with severe primary and secondary pulmonary hypertension. The authors noted a significant reduction in pulmonary vascular resistance and a moderate increase in cardiac index. The reasonability of using PDE-5 inhibitors in the treatment of pulmonary hypertension of different origins was confirmed by other researchers.

Interesting results have also been shared by Doctor Green research group. The scientists have managed to demonstrate a decrease in size of the area of myocardial infarction in the rabbit as a result of intravenous sildenafil citrate injection. The inventors have found that this effect is eliminated by the introduction of 5-hydroxydecanoate, an inhibitor of the mitochondrial ATP-sensitive potassium channels, allowing them to bind the beneficial effects of sildenafil to the action on these channels. In studies in patients with heart failure, Caverta has a mild antiplatelet effect.

Administration

caverta-50mgAs a rule, the recommendations on how to use Caverta tend to be similar: the dosage is selected equally in case of good tolerability. Thus, the starting dose of 50 mg is usually prescribed, following by an adjustment (either a reduction to 25 mg, or an increase to 100 mg), depending on the effect and tolerability. Sildenafil is taken 1 time a day, approximately 1 hour before anticipated sexual activity.

The effect of the drug begins after 40-60 minutes after taking; a pronounced action is observed within 3-5 hours. An overall tolerability level is above average. Major side effects are characterized by transient and mild or moderate severity of headache (7%), redness of the face and neck (7%), dyspepsia (1.8%), nasal congestion (1.4%) , blurred vision (1.2%). Very rare side effects of sildenafil cause treatment discontinuation; though they are more likely to occur (80%) in the dosages of 100+ mg. The only contraindication to the use of sildenafil is treatment with nitrates because of the risk of hypotension.

However, despite the high efficacy of sildenafil (85%), a group of patients (15-42%) who considered the therapy with this drug to be poorly effective or ineffective at all.

In recent years, growing interest attracted by the possibility of sildenafil in various diseases, in addition to erectile dysfunction.

Pharmacological effect

cavertaThe preparation is produced by a far-famed Ranbaxy laboratory. The clinical efficacy of Caverta 25 mg has been evaluated in numerous studies conducted worldwide. Carson research group pooled data from 11 double-blind, placebo-controlled trials involving a total of almost 3,000 patients with erectile dysfunction.

12 weeks after the start of the course the improved erections were observed in 76% of subjects receiving sildenafil citrate and 22% on placebo, while the percentage of successful sexual intercourse attempts equaled 66% and 26% in the first and second group, respectively. The efficacy of different doses of sildenafil was 65% for the 25 mg, 74% for the 50 mg and 82% for the 100 mg.

The drug is effective in patients with both organic and psychogenic erectile dysfunction. High efficacy of sildenafil observed in different age groups. For example, among patients aged under and over 65 years the efficacy of sildenafil was estimated at 77.6% and 69.2%, respectively.

According to Lue research group, the efficacy of sildenafil equals 66-90% in cases of organic ED with good tolerability. The efficacy of sildenafil in patients with diabetes ranges from 59-61%, hypertension – 65-70%, depressive states – 59-76%, spinal cord injuries – up to 65%. Caverta is characterized by high effectiveness, in both psychogenic and organic forms of erectile dysfunction, good tolerability and absence of significant side effects, compatibility with many drugs from various pharmacological groups allow regarded as the most acceptable sildenafil pharmacological agent for sexual patient adaptation.